High Quality Content by WIKIPEDIA articles! Acepromazine or acetylpromazine (more commonly known as ACP, Ace, or by the trade names Atravet or Acezine 2 , number depending on mg/ml dose) is a phenothiazine derivative antipsychotic drug. It was first used in humans in the 1950s, but is now little used in humans (the closely related analogue, chlorpromazine, is still used as an antipsychotic in humans). Acepromazine is frequently used in animals as a sedative and antiemetic. Its principal value is in quietening and calming anxious animals. The standard pharmaceutical preparation, acepromazine maleate, is used extensively in horses, dogs, and cats; especially as a preanesthetic agent often in conjunction with atropine, and often an opiate such as morphine or buprenorphine. Its potential for cardiac effects can be profound and as such is not recommended for use in geriatric or debilitated animals In these cases it is often substituted with midazolam or left out of the preanesthetic medication altogether.

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