High Quality Content by WIKIPEDIA articles! State Route 5 is a north–south state highway is the western part of the State of Alabama. While it once extended—prior to the renumbering of the highways of Alabama in 1957—from Mobile north to Tennessee, and was one of the major routes between Mobile and Birmingham, it has since been shortened to about half of its former length, and superseded by newer highways such as Interstate 65 and State Route 157.