Argonne National Laboratory is the first science and engineering research national laboratory in the United States, receiving this designation on July 1, 1946. It is the largest national lab by size and scope in the Midwest. A multipurpose laboratory led by director Eric Isaacs, Argonne maintains a broad portfolio in basic science research, energy storage and renewable energy, environmental sustainability, and national security. It is managed for the United States Department of Energy by UChicago Argonne, LLC, which is composed of the University of Chicago and Jacobs Engineering Group Inc. Argonne is a part of the expanding Illinois Technology and Research Corridor. The lab is located on 1,700 acres (6.9 km ) in DuPage County, 25 miles (40 km) southwest of Chicago, Illinois, on Interstate 55, completely encircled by Waterfall Glen Forest Preserve. When it was first established it was known as the University of Chicago's Metallurgical Laboratory (Met Lab), and it was previously located within Red Gate Woods. Early in its history, the lab was part of the Manhattan Project, which built the first atomic bomb.

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