Издательство: | Книга по требованию |
Дата выхода: | июль 2011 |
ISBN: | 978-6-1306-1363-1 |
Объём: | 68 страниц |
Масса: | 123 г |
Размеры(В x Ш x Т), см: | 23 x 16 x 1 |
Asymmetric induction (also enantioinduction) in stereochemistry describes the preferential formation in a chemical reaction of one enantiomer or diastereoisomer over the other as a result of the influence of a chiral feature present in the substrate, reagent, catalyst or environment. Asymmetric induction is a key element in asymmetric synthesis. Asymmetric induction was introduced by Emil Fischer based on his work on carbohydrates. Several types of induction exist. Internal asymmetric induction makes use of a chiral center bound to the reactive center through a covalent bond and remains so during the reaction. The starting material is often derived from chiral pool synthesis. In relayed asymmetric induction the chiral information is introduced in a separate step and removed again in a separate chemical reaction. Special synthons are called chiral auxiliaries. In external asymmetric induction chiral information is introduced in the transition state through a catalyst of chiral ligand. This method of asymmetric synthesis is economically most desirable.
Данное издание не является оригинальным. Книга печатается по технологии принт-он-деманд после получения заказа.