High Quality Content by WIKIPEDIA articles! A biochemical cascade is a series of chemical reactions in which the products of one reaction are consumed in the next reaction. These cascades facilitate the transformation or generation of complex molecules in small steps. At each step, various controlling factors are involved to regulate cellular reactions, responding effectively to cues about their changing internal and external environments. Chemical reactions are orchestrated by complex molecular networks, which consist of proteins/enzymes or RNAs (second messengers), connected by activation or synthesis in biological processes.