High Quality Content by WIKIPEDIA articles! Blood-C is a 2011 anime/manga series and 2012 film produced in collaboration by Studio Production I.G and manga creators CLAMP. This is Production I.G`s second anime series related to the Blood franchise, the first being Blood+, which aired in 2005–2006. An animated film, Blood-C: The Last Dark was released in Japanese theatres on June 2, 2012.