Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Bohemic acid is a mixture of chemical compounds which is obtained by fermentation of actinobacteria species in the Actinosporangium genus (Actinoplanaceae). It honors the Puccini opera La Boheme and many individual components of the acid carry the names of the personages of La Boheme. Most of those components are antitumor agents and anthracycline antibiotics active against Gram-positive bacteria. The median lethal dose (LD50) of marcellomycin depends strongly on the animal and varies from a few mg/kg of body weight (dogs) to 20 mg/kg (Suiss-Webster mice, intravenal injection), the major site of toxicity being the gastrointestinal tract. Bohemamine has several structural varieties and derivatives, such as bohemamine B (C14H20N2O3), bohemamine C (C14H21N2O3), and 5-chlorobohemamine C (C14H20ClN2O3). None of them showed antibiotic, antifungal or antitumor activity.

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