High Quality Content by WIKIPEDIA articles! State Route 46 (SR 46) is an east–west state highway in the U.S. state of California. It is a major crossing of the Coast Ranges, connecting SR 1 on the Central Coast near Cambria and US 101 in Paso Robles with SR 99 at Famoso in the San Joaquin Valley. East of Paso Robles, where it carried U.S. Route 466 until 1964, SR 46 is part of the California Freeway and Expressway System, though it is mostly a two-lane highway. The highway from SR 1 to SR 41 near Cholame is an eligible State Scenic Highway, but has not been designated as such.