Издательство: | Книга по требованию |
Дата выхода: | июль 2011 |
ISBN: | 978-6-1337-2675-8 |
Объём: | 72 страниц |
Масса: | 129 г |
Размеры(В x Ш x Т), см: | 23 x 16 x 1 |
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Deamidation is a chemical reaction in which an amide functional group is removed from an organic compound. In biochemistry, the reaction is important in the degradation of proteins because it damages the amide-containing side chains of the amino acids asparagine and glutamine. In the biochemical deamidation reaction, the side chain of an asparagine attacks the following peptide group, forming a symmetric succinimide intermediate. The symmetry of the intermediate results in two products of its hydrolysis, either aspartate or in isoaspartate, which is a beta amino acid. This process is considered a deamidation because the amide in the asparagine side chain is replaced by a carboxylate group. However, a similar reaction can occur in aspartate side chains, yielding a partial conversion to isoaspartate
Данное издание не является оригинальным. Книга печатается по технологии принт-он-деманд после получения заказа.