High Quality Content by WIKIPEDIA articles! The December 2000 Tuscaloosa tornado was a destructive tornado that hit communities south and east of Tuscaloosa, Alabama on December 16, 2000. The F4 rated tornado caused the deaths of 11 people while injuring over 125 others. It was the strongest tornado to hit the state of Alabama in the month of December since 1950 and the strongest of a moderate tornado outbreak that took place across the Southeastern corner of the United States from Mississippi to North Carolina.