Dr. Mario 64 is a puzzle game based on the original Dr. Mario. It was developed and published by Nintendo, released for the Nintendo 64 in 2001, and is an enhanced remake of the original Dr. Mario, which was released for the NES and Game Boy in 1990. It was re- released along with Panel de Pon and Yoshi's Cookie in a GameCube video game called Nintendo Puzzle Collection in 2003, which was only released in Japan.

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