High Quality Content by WIKIPEDIA articles! Dr. No is the sixth novel in Ian Fleming`s James Bond series, first published in the UK by Jonathan Cape on 31 March 1958. The story centres on Bond`s investigation into the disappearance in Jamaica of a fellow MI6 operative, Commander John Strangways and his secretary, Mary Trueblood. He establishes that Strangways had been investigating Dr. No, a Chinese operator of a guano mine on the Caribbean island of Crab Key; Bond travels to the island to investigate further. It is on Crab Key that Bond first finds Honeychile Rider and then Dr. No himself.