ISBN: | 978-5-5105-9373-0 |
High Quality Content by WIKIPEDIA articles! Ethylene glycol poisoning is caused by the ingestion of ethylene glycol (the primary ingredient in both automotive antifreeze and hydraulic brake fluid). It is a toxic, colorless, odorless, almost nonvolatile liquid with a sweet taste and is occasionally consumed by children and dogs for its sweetness. Following ingestion the symptoms of poisoning follow a three step progression starting with intoxication and vomiting, before causing metabolic acidosis, cardiovascular dysfunction, and finally acute kidney failure. The major cause of toxicity is not the ethylene glycol itself but its metabolites. The major metabolites causing toxicity are glycolic acid and oxalic acid.