High Quality Content by WIKIPEDIA articles! Francisco Javier Eugenio de Santa Cruz y Espejo (Royal Audiencia of Quito, 1747–1795) was a medical pioneer, writer and lawyer of mestizo origin in colonial Ecuador. Although he was a notable scientist and writer, he stands out as a polemicist who inspired the separatist movement in Quito. He is regarded as one of the most important figures in colonial Ecuador. He was Quito`s first journalist and hygienist. As a journalist he spread enlightened ideas in the Royal Audiencia, and as a hygienist he composed an important treatise about sanitary conditions in colonial Ecuador that included interesting remarks about microorganisms and the spreading of disease.