Evaluation antioxidant activity. Synthesis and antioxidant properties of some benzothienopyridine and benzothienopyrimidone derivatives

Evaluation antioxidant activity. Synthesis and antioxidant properties of some benzothienopyridine and benzothienopyrimidone derivatives

Raghunath Toche

     

бумажная книга



Издательство: Книга по требованию
Дата выхода: июль 2011
ISBN: 978-3-8433-5872-9
Объём: 68 страниц
Масса: 123 г
Размеры(В x Ш x Т), см: 23 x 16 x 1

Two different series of benzothienopyridines and benzothienopyrimidines were synthesized in good yields and their structures were established by spectroscopic characterization. Free radical scavenging effects of synthesized compounds were also evaluated experimentally against DPPH and ABTS radicals. In the series; 2-amino-benzo[b]thiophene-3-carboxamide 2 and 2-pyridine-2-phenyl-,5,6,7,8,9-hexahydro- benzo[4,5]thieno[2,3-d]pyrimidin-4- ylamine 6d are showed the highest radical scavenging activity against both radicals and their radical scavenging effects were comparable to the reference standard Trolox.

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