High Quality Content by WIKIPEDIA articles! Florida is an unincorporated village in Monroe County, Missouri, United States. It is located at the intersection of Missouri Highway 107 and County road "U" on the shores of Mark Twain Lake. The population was nine residents according to the 2000 United States Census. Following the 2010 Census the village was reported as uninhabited. The Mark Twain Birthplace State Historic Site is located in Florida, with Mark Twain State Park nearby.