Glyphosate (N-(phosphonomethyl) glycine) is a broad-spectrum systemic herbicide used to kill weeds, especially perennials. It is typically sprayed and absorbed through the leaves, injected into the trunk, or applied to the stump of a tree, or broadcast or used in the cut-stump treatment as a forestry herbicide. Initially patented and sold by Monsanto Company in the 1970s under the tradename Roundup, its U.S. patent expired in 2000. Glyphosate is the most used herbicide in the USA. In the US, 5-8 million pounds are used every year on lawns and yards and 85-90 million pounds are used annually in US agriculture.

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