High Quality Content by WIKIPEDIA articles! Gregory House, M.D., or simply referred to as House, is a fictional antihero and title character of the American television series House, played by Hugh Laurie. He is the Chief of Diagnostic Medicine at the fictional Princeton-Plainsboro Teaching Hospital, where he leads a team of diagnosticians. House`s character has been described as a "misanthrope," a "cynic," a narcissist and a "curmudgeon".