High Quality Content by WIKIPEDIA articles! The HIV Vaccine Trials Network (HVTN) is a non-profit organization which connects physicians and scientists with activists and community educators for the purpose of conducting clinical trials seeking a safe and effective HIV vaccine. Collaboratively, research professionals and laypeople review potential vaccines for safety, immune response, and efficacy. The HVTN is the only HIV vaccine research network sponsored nationwide by the American government. It also manages the only large-scale HIV vaccine research trial network in Africa.