High Quality Content by WIKIPEDIA articles! Indole alkaloids is a class of alkaloids containing a structural moiety of indole; many indole alkaloids also include isoprene groups. Containing more than 4100 known different compounds, it is one of the largest classes of alkaloids. Many of them possess significant physiological activity and some of them are used in medicine. The amino acid tryptophan is the biochemical precursor of indole alkaloids. The plants that are rich in non-isoprenoid indole alkaloids include harmal (Peganum harmala), which contains harmane, harmine and harmaline, and Calabar bean (Physostigma venenosum) containing physostigmine. Some members of the family Convolvulaceae, in particular Ipomoea violacea and Turbina corymbosa, contain derivatives of lysergic acid. Despite the considerable structural diversity, most of monoterpenoid indole alkaloids is localized in three families of dicotyledon plants: Apocynaceae (genera Alstonia, Aspidosperma, Rauwolfia and Catharanthus), Rubiaceae (Corynanthe) and Loganiaceae (Strychnos).

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