High Quality Content by WIKIPEDIA articles! Instituto Butantan is a Brazilian biomedical research center affiliated to the Sao Paulo State Secretary of Health. It is located near the campus of the University of Sao Paulo, in the city of the same name. The Institute was founded by the Brazilian physician and biomedical scientist Vital Brazil in 1901, according to Pasteur Institute paradigm, i.e., by combining in the same institution medical research, the transfer of the results to society as health products, and self-financing through this later activity. Its foundation was a reaction to the outbreak of bubonic plague in the city of Santos

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