Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Four major high-throughput gene-targeted mutagenesis programs in Knockout mice are currently underway around the world: the National Institutes of Health (NIH)-sponsored Knockout Mouse Program (KOMP) and state-funded Texas Institute for Genomic Medicine (TIGM) in the U.S., the North American Conditional Mouse Mutagenesis (NorCOMM) Program in Canada, and the European Union Conditional Mouse Mutagenesis (EUCOMM) Programme in Europe. As a result of these efforts, the number of mouse genome-based genetic resources, including data (annotated gene data, phenotypic descriptions, etc) and biological collections (knockout mice, cryopreserved germplasm, embryonic stem cell (ES) clones, targeting vectors) are poised to increase dramatically over the next several years.

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