High Quality Content by WIKIPEDIA articles! In the U.S. state of New Mexico, Interstate 25 (I-25) follows the north–south corridor through Albuquerque and Santa Fe. It replaced U.S. Route 85, which is no longer signed, but still exists in route logs sharing the I-25 alignment. I-25 starts in New Mexico at an interchange with I-10 in Las Cruces and extends roughly 460 miles before reaching Colorado. I-25 passes through principally rural land through central New Mexico and passes through or near the cities of Las Cruces, Truth or Consequences, Socorro, Belen, Albuquerque, Santa Fe, Las Vegas, and Raton.