High Quality Content by WIKIPEDIA articles! Interstate 71 (I-71) is an Interstate Highway in the Great Lakes/Midwestern and Southeastern region of the United States. Its southern terminus is at an interchange with Interstate 64 and Interstate 65 (the Kennedy Interchange) in Louisville, Kentucky. Its northern terminus is at an interchange with Interstate 90 in Cleveland, Ohio. I-71 runs concurrently with Interstate 75 from a point about twenty miles (30 km) south of Cincinnati, Ohio into downtown Cincinnati. Almost three quarters of the route lies east of I-75, thereby putting it out of its proper place in the Interstate grid.