High Quality Content by WIKIPEDIA articles! Interstate 80 (I-80) is the second-longest Interstate Highway in the United States, following Interstate 90. It is a transcontinental artery running from downtown San Francisco, California to Teaneck, New Jersey in the New York City Metropolitan Area. I-80 is the Interstate Highway that most closely approximates the route of the historic Lincoln Highway, the first road across America. The highway roughly traces other historically significant travel routes in the Western United States: the Oregon Trail across Wyoming and Nebraska, the California Trail across most of Nevada and California, and except in the Great Salt Lake area, the entire route of the First Transcontinental Railroad.