High Quality Content by WIKIPEDIA articles! Interstate 95 in Maryland is a major highway that runs diagonally from northeast to southwest, from Maryland`s border with Delaware, to the Woodrow Wilson Bridge, briefly entering the District of Columbia before reaching Virginia. The route is one of the most heavily traveled Interstate Highways in Maryland, especially between Baltimore and Washington, D.C., despite alternate routes along the corridor, such as the Baltimore-Washington Parkway, U.S. 1, and U.S. Route 29. Portions of the highway are tolled.