High Quality Content by WIKIPEDIA articles! Isotopologues are molecules that differ only in their isotopic composition. Simply, the isotopologue of a chemical species has at least one atom with a different number of neutrons to the parent. An example is water, where some of its hydrogen-related isotopologues are: "light water", "semi-heavy water" with the deuterium isotope in equal proportion to protium, "heavy water" with two deuterium isotopes of hydrogen per molecule, and "super-heavy water" or tritiated water, where the hydrogen atoms are replaced with tritium isotopes. Oxygen-related isotopologues of water include the commonly available form of heavy-oxygen water and the more difficult to separate version with the 17O isotope. Both elements may be replaced by isotopes, for example in the doubly-labeled water isotopologue D218O.

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