High Quality Content by WIKIPEDIA articles! The IUD with progestogen, intrauterine system (IUS), or IntraUterine Contraceptive (IUC) is a long-acting reversible hormonal contraceptive device that is placed in the uterus. An IUS has a hormone cylinder that releases a progestin (a synthetic progestogen) called levonorgestrel. The only brand currently available is the T-frame LNG-20 IUS, marketed as Mirena by Bayer.