High Quality Content by WIKIPEDIA articles! The Laboratory of Neuro Imaging (LONI) is a research laboratory within the Department of Neurology at the UCLA David Geffen School of Medicine. The laboratory conducts a wide variety of brain imaging studies of normal brain anatomy and function, development, aging, and disease. Historically, research at LONI has focused on design, development, validation and wide dissemination of software tools for use in understanding the relationships between brain structure and function across space, time and scale. In particular, work has been conducted toward the construction of multidimensional brain atlases seeking to promote computationally efficient representations of brain anatomy, function and physiology in a standardized 3D coordinate system. Brain imaging modalities include MRI, fMRI, Diffusion Tensor Imaging, Magnetic Resonance Spectroscopy, Positron Emission Tomography, Optical Intrinsic Signal, among other means for gathering spatially-based neurophysiological signals.