High Quality Content by WIKIPEDIA articles! Lady Macbeth is a fictional character in Shakespeare`s Macbeth (c.1603–1607). She is the wife to the play`s protagonist, Macbeth, a Scottish nobleman. After goading him into committing regicide, she becomes Queen of Scotland, but later suffers pangs of guilt for her part in the crime. She dies off-stage in the last act, an apparent suicide.