High Quality Content by WIKIPEDIA articles! Lisa Marie Simpson is a fictional main character in the animated television series The Simpsons. She is the middle child of the Simpson family. Voiced by Yeardley Smith, Lisa first appeared on television in The Tracey Ullman Show short "Good Night" on April 19, 1987. Cartoonist Matt Groening created and designed her while waiting to meet James L. Brooks. Groening had been invited to pitch a series of shorts based on his comic Life in Hell, but instead decided to create a new set of characters. He named the elder Simpson daughter after his younger sister Lisa Groening. After appearing on The Tracey Ullman Show for three years, the Simpson family were moved to their own series on Fox, which debuted on December 17, 1989.