High Quality Content by WIKIPEDIA articles! Blood+ is an animated television series created by Production I.G. It premiered in Japan on October 8, 2005 on MBS/TBS, and continued with episodes every week (except on December 31, 2005) until September 23, 2006. The series simultaneously aired on Animax, Sony`s Japanese anime satellite channel, with its networks in Southeast Asia and South Asia airing the series later. It was directed by Junichi Fujisaku and features original character designs by Chizu Hashii. Fifty consecutive episodes were aired spanning four distinct seasons. Each season is differentiated by opening and ending themes from a variety of artists, with the final episode using the season one ending theme.