High Quality Content by WIKIPEDIA articles! The episodes from the anime Fullmetal Alchemist are based on Fullmetal Alchemist manga by Hiromu Arakawa. Set in a fictional universe in which alchemy is one of the most advanced scientific techniques known to man, the story follows Edward and Alphonse Elric, two alchemist brothers, who want to recover parts of their bodies lost in an attempt to bring their mother back to life through alchemy.