High Quality Content by WIKIPEDIA articles! This is a list of the top 300 Major League Baseball home run hitters. In the sport of baseball, a home run is a hit in which the batter scores by circling all the bases and reaching home plate in one play, without the benefit of a fielding error. This can be accomplished either by hitting the ball out of play while it is still in fair territory (a conventional home run), or by an inside the park home run.