High Quality Content by WIKIPEDIA articles! "Little Girl in the Big Ten" is the twentieth episode of The Simpsons’ thirteenth season. It originally aired on the Fox network in the United States on May 12, 2002. In the episode, after seeing John F. Kennedy in a hallucination during gym class, Lisa befriends two college students in order to join college. Meanwhile, after being bitten by a mosquito from a Chinese made toy, Bart is infected with the "panda virus" and in a plastic bubble to prevent others from infection.