High Quality Content by WIKIPEDIA articles! Lost in Yonkers is a 1991 Pulitzer Prize-winning play by Neil Simon. After eleven previews, the Broadway production, produced by Emanuel Azenberg and directed by Gene Saks, opened on February 21, 1991 at the Richard Rodgers Theatre, where it ran for 780 performances. The original cast included Irene Worth as Grandma, Mercedes Ruehl as Bella, Kevin Spacey as Louie, Lauren Klein as Gert, Danny Gerard as Arty, Jamie Marsh as Jay, and Mark Blum as Eddie.