High Quality Content by WIKIPEDIA articles! Lucrezia Borgia (18 April 1480 – 24 June 1519) was the illegitimate daughter of Rodrigo Borgia, the powerful Renaissance Valencian who later became Pope Alexander VI, and Vannozza dei Cattanei. Her brothers included Cesare Borgia, Giovanni Borgia, and Gioffre Borgia. It is often suggested that Cesare and Lucrezia may have had an incestuous relationship.