High Quality Content by WIKIPEDIA articles! M-221 is a short state trunkline highway in the Upper Peninsula (UP) of the US state of Michigan that connects M-28 with the community of Brimley and Brimley State Park. The highway was originally part of M-28 until the 1940s when it was briefly a local road. It has been a state highway again since it was designated as M-221 in 1945.