High Quality Content by WIKIPEDIA articles! M-27 is a north–south state trunkline highway in the extreme north of the Lower Peninsula of the US state of Michigan. The route runs between Interstate 75 (I-75) just north of Indian River and Cheboygan, where it meets US Highway 23 (US 23) near Lake Huron. It remains as a relic of the old US 27 which disappeared north of Grayling after being supplanted by I-75, which lies close to old US 27 between Grayling and Indian River.