High Quality Content by WIKIPEDIA articles! M-45 is a state trunkline highway in the US state of Michigan that is also called Lake Michigan Drive. The highway runs from Agnew near Lake Michigan to the west side of Grand Rapids in the western Lower Peninsula. Lake Michigan Drive continues in each direction from M-45`s termini, extending west of US Highway 31 (US 31) and east of Interstate 196 (I-196). In between, the road runs through rural and suburban areas of Ottawa and Kent counties, including the main campus of Grand Valley State University in Allendale. Lake Michigan Drive was originally part of M-50 until the mid-1960s. Previously in the 1920s and 30s, the M-45 number was designated along a highway in the Upper Peninsula (UP).