High Quality Content by WIKIPEDIA articles! mDia1 (also known as Dia1, Drf1 for Diaphanous-related formin-1, Diaph1, KIAA4062, p140mDia, mKIAA4062, D18Wsu154e) is a protein. It is the mouse version of the diaphanous homolog 1 of Drosophila. It belongs to the protein family called the formins and is a Rho effector. It localizes to the mitotic spindle and midbody, plays a role in stress fiber and filopodia formation, phagocytosis, activation of serum response factor, a transcription factor, and formation of adherens junction. mDia1 accelerates actin nucleation and elongation by interacting with barbed ends (fast-growing ends) of actin filaments. The gene encoding mDia1 is located on Chromosome 18 of Mus musculus and named Diap1.