Издательство: | Книга по требованию |
Дата выхода: | июль 2011 |
ISBN: | 978-3-8381-1324-1 |
Объём: | 140 страниц |
Масса: | 233 г |
Размеры(В x Ш x Т), см: | 23 x 16 x 1 |
Modelling and simulation of tumor growth is one of the challenging frontiers of applied mathematics. We study in this work a mathematical model for the growth of nonnecrotic tumors in different regimes of vascularisation. The tumor is treated as an incompressible fluid, tissue elasticity is neglected, and the mathematical model is a moving boundary problem. In the radially symmetric case we establish the existence of a unique radially symmetric stationary solution and show, that if the initial tumor is radially symmetric, there exists a unique radially symmetric solution of the problem, which exists for all times. The asymptotic behaviour of this solution it is also discussed. If we consider star-shaped initial tumor domains, we can re-express the mathematical model as an abstract evolution equation. Using general results for parabolic equations we prove the well-posedness of the model. The stability properties of the radially symmetric equilibrium are studied using the principle of linearised stability . Finally, we show, via a bifurcation argument, that there exist also other stationary solutions of the problem, which are no longer radially symmetric.
Данное издание не является оригинальным. Книга печатается по технологии принт-он-деманд после получения заказа.