High Quality Content by WIKIPEDIA articles! It is now widely accepted that -opioid receptor (partial) agonists have dissociative and deliriant effects, as exemplified by salvinorin A. These effects are generally undesirable in medicinal drugs and could have had frightening or disturbing effects in the tested humans. It is thought that the hallucinogenic effects of drugs such as butorphanol, nalbuphine, and pentazocine serve to limit their opiate abuse potential. In the case of salvinorin A, a structurally novel neoclerodane diterpene -opioid receptor agonist, these hallucinogenic, more specifically deliriant and dissociative, effects are sought after, even though the substance is inherently dysphoric. While salvinorin A is considered a hallucinogen, it is not a psychedelic, and its effects are qualitatively different than those produced by the classical psychedelic hallucinogens such as LSD or mescaline.

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