High Quality Content by WIKIPEDIA articles! Thomas A. Anderson (alias Neo, also known as The One or The Anomaly) is a fictional character and the main protagonist in The Matrix franchise, as well as having a cameo in The Animatrix short film, Kid`s Story. He was portrayed by Keanu Reeves in The Matrix Trilogy and The Animatrix. Andrew Bowen provided Neo`s voice in The Matrix: Path of Neo. In 2008, Neo was selected by Empire as the 16th greatest movie character of all time. Neo is also an anagram of One, a reference to his destiny of being "The One" who would bring peace.