High Quality Content by WIKIPEDIA articles! Night at the Museum is a 2006 fantasy adventure-comedy film based on the 1993 children`s book The Night at the Museum by Milan Trenc. It follows a divorced father trying to settle down, impress his son, and find his destiny. He applies for a job as a night watchman at New York City`s American Museum of Natural History and subsequently discovers that the exhibits, animated by a magical Egyptian artifact, come to life at night.