High Quality Content by WIKIPEDIA articles! In chemistry, a NONOate is a compound having the chemical formula R1R3N-(NO?)-N=O, where R1 and R2 are alkyl groups. One example for this is 1,1-diethyl-2-hydroxy-2-nitrosohydrazine, or diethylamine dinitric oxide. These compounds are unusual in having three sequential nitrogen atoms: an amine functional group, a bridging NO? group, and a terminal nitrosyl group. In contact with water, these compounds release NO (nitric oxide). Most NONOates are stable in alkaline solution above pH 8.0 (e. g. 10 mM NaOH) and can be stored at ?20 °C in this way for the short term. To generate NO from NONOates, the pH is lowered accordingly.

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