High Quality Content by WIKIPEDIA articles! The Office of Criminal Investigations (OCI) was established to provide the Food and Drug Administration (FDA) with a specific Office to conduct and coordinate criminal investigations. OCI special agents employ customary federal law enforcement methods and techniques in the investigation of suspected criminal violations of the Federal Food, Drug, and Cosmetic Act, the Federal Anti-Tampering Act, and other related federal statutes. OCI investigations concentrate on significant violations of these laws, with a priority on conduct that may present a danger to the public health. OCI is a relatively small agency, employing approximately 180 Special Agents.