High Quality Content by WIKIPEDIA articles! Ohio Brush Creek is a 59.9-mile-long (96.4 km)tributary of the Ohio River in southern Ohio in the United States. Via the Ohio River, it is part of the watershed of the Mississippi River, draining an area of 435 square miles (1,130 km2). According to the Geographic Names Information System, it has also been known historically as "Brush Creek," "Elk Creek," and "Little Scioto River"