High Quality Content by WIKIPEDIA articles! The Ospedale Maggiore, traditionally named Ca` Granda (i.e. Big House), is a building in the center of Milan, northern Italy, constructed to house one of the first community hospitals, the largest such undertaking of the fifteenth century. Commissioned by Francesco Sforza in 1456 and designed by Antonio Filarete it is among the first examples of Renaissance architecture in Lombardy.