High Quality Content by WIKIPEDIA articles! The Parvoviridae family includes the smallest known viruses, and some of the most environmentally resistant. They were discovered during the 1960s and affect vertebrates and insects. Parvoviridae have a genome consisting of single-stranded DNA and an icosahedral capsid. Parvovirus B19 was the first human parvovirus to be discovered and is best known for causing a childhood exanthem called "fifth disease" (erythema infectiosum), although it is also associated with other diseases including arthritis. Parvovirus RA-1 had originally also been associated with rheumatoid arthritis, but this is now thought to have been an error due to laboratory contamination.

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